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| HCG Profile |
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HCG - HUMAN CHORIONIC GONADOTROPIN
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HCG, is not an anabolic/androgenic steroid but a natural protein
hormone which develops in the placenta of a pregnant woman. HCG is
formed in the placenta immediately after nidation. It has
luteinizing characteristics since it is quite similar to the
luteinizing hormone LH in the anterior pituitary gland. During the
first 6-8 weeks of a pregnancy the formed HCG allows for continued
production of estrogens and gestagens in the yellow bodies (corpi
luteum). Later on, the placenta itself produces these two hormones.
HCG is manufactured from the urine of pregnant women since it is
excreted in unchanged form from the blood via the womans urine,
passing through the kidneys. The commercially available HCG is sold
as a dry substance and can be used both in men and women. In women
injectable HCG allows for owlation since it influences the last
stages of the development of the ovum, thus stimulating ovulation.
It also helps produce estrogens and yellow bodies.
The fact that exogenous HCG has characteristics almost identical to
those of the luteinizing hormone (LH) which, as mentioned, is
produced in the hypophysis, makes HCG so very interesting for
athletes. In a man the luteinizing hormone stimulates the Leydigs
cells in the testes; this in turn stimulates production of
androgenic hormones (testosterone). For this reason athletes use
injectable HCG to increase the testosterone production. HCG is often
used in combination with anabolic/androgenic steroids during or
after treatment. As mentioned, oral and injectable steroids cause a
negative feedback after a certain level and duration of usage. A
signal is sent to the hypothalamohypophysial testicular axis since
the steroids give the hypothalamus an incorrect signal. The
hypothalamus, in turn, signals the hypophysis to reduce or stop the
production of FSH (follicle stimulating hormone) and of LH. Thus,
the testosterone production decreases since the
testosterone-producing Leydigs cells in the testes, due to decreased
LH, are no longer sufficiently stimulated. Since the body usually
needs a certain amount of time to get its testosterone production
going again, the athlete, after discontinuing steroid compounds,
experiences a difficult transition phase which often goes hand in
hand with a considerable loss in both strength and muscle mass.
Administering HCG directly after steroid treatment helps to reduce
this condition because HCG increases the testosterone production in
the testes very quickly and reliably. In the event of testicular
atrophy caused by megadoses and very long periods of usage, HCG also
helps to quickly bring the testes back to their original condition
(size). Since occasional injections of HCG during steroid intake can
avoid a testicular atrophy, many athletes use HCG for two to three
weeks in the middle of their steroid treatment. It is often observed
that during this time the athlete makes his best progress with
respect to gains in both strength and muscle mass. The reasons for
this is clear. On the one hand, by taking HCG the athletes own
testosterone level immediately jumps up and, on the other hand, a
large concentration of anabolic substances in the blood is induced
by the steroids. Many bodybuilders, powerlifters, and weightlifters
report a lower sex drive at the end of a difficult workout cycle,
immediately before or after a competition, and especially toward the
end of a steroid treatment. Athletes who have often taken steroids
in the past usually accept this fact since they know that it is a
temporary condition. Those, however who are on the juice all year
round, who might suffer psychological consequences or who would
perhaps risk the breakup of a relationship because of this should
consider this drawback when taking HCG in regular intervals. A
reduced libido and spermatogenesis due to steroids in most cases,
can be successfully cured by treatment with HCG.
Most athletes, however, use HCG at the end of a treatment in order
to avoid a "crash," that is, to achieve the best possible transition
into "natural training." A precondition, however, is that the
steroid intake or dosage be reduced slowly and evenly before taking
HCG. Although HCG causes a quick and significant increase of the
endogenic plasmatestosterone level, unfortunately it is not a
perfect remedy to prevent the loss of strength and mass at the end
of a steroid treatment. The athlete will only experience a delayed
re-adjustment, as has often been observed. Although HCG does
stimulate endogenous testosterone production, it does not help in
reestablishing the normal hypothalamic/pituitary testicular axis.
The hypothalamus and pituitary are still in a refractory state after
prolonged steroid usage, and remain this way while HCG is being
used, because the endogenous testosterone produced as a result of
the exogenous HCG represses the endogenous LH production. Once the
HCG is discontinued, the athlete must still go through a
re-adjustment period. This is merely delayed by the HCG use. For
this reason experienced athletes often take Clomid and Clenbuterol
following HCG intake or they immediately begin another steroid
treatment. Some take HCG merely to get off the "steroids" for at
least two to three weeks.
Many bodybuilders, unfortunately, are still of the opinion that HCG
helps them become harder while preparing for a competition by
breaking down subcutaneous fat so that indentations and vascularity
are better exposed. The HCG package insert states clearly that HCG
has no known effect of fat mobilization, appetite or sense of
hunger, or body fat distribution. HCG has not been demonstrated to
be effective adjunctive therapy in the treatment of obesity, it does
not increase fat losses beyond that resulting from caloric
restriction.
Athlete should inject one HCG ampule (5000 I.U.) every 5 days. Since
the testosterone level, as explained, remains considerably elevated
for several days, it is unnecessary to inject HCG more than once
every 5 days. The relative dose is at the discretion of the athlete
and should be determined based on the duration of his previous
steroid intake and on the strength of the various steroid compounds.
Athletes who take steroids for more than three months and athletes
who use primarily the highly androgenic steroids such as Anadrol,
Sustanon Cypionate
, Dianabol (D-bol), etc. should take a relatively high dosage. The
effective dosage for athletes is usually 2000-5000 I.U. per
injection and should as already mentioned be injected every 5 days.
HCG should only be taken for a 4 weeks maximum.
If HCG is taken by male athletes over many weeks and in high
dosages, it is possible that the testes will respond poorly to a
later HCG intake and a release of the body own LH. This could result
in a permanent inadequate gonadal function. Cycles on the HCG should
be kept down to around 3 weeks at a time with an off cycle of at
least a month in between. For example, one might use the HCG for 2
or 3 weeks in the middle of a cycle, and for 2 or 3 weeks at the end
of a cycle. It has been speculated that the prolonged use of HCG
could permanently, repress the body own production of gonadotropins.
This is why short cycles are the best way to go.
HCG can in part cause side effects similar to those of injectable
testosterone. A higher testosterone production also goes hand in
hand with an elevated estrogen level which could result in
gynecomastia. This could manifest itself in a temporary growth of
breasts or reinforce already existing breast growth in men.
Farsighted athletes thus combine HCG with an antiestrogen. Male
athletes also report more frequent erections and an increased sexual
desire. In high doses it can cause acne vulgaris and the storing of
minerals and water. The last point must especially be observed since
the water retention which is possible through the use of HCG could
give the muscle system a puffy and watery appearance. Athletes who
have already increased their endogenous testosterone level by taking
Clomid and intend subsequently to take HCG could experience
considerable water retention and distinct feminization symptoms (gynecomastia,
tendency toward fat deposits on the hips). This is due to the fact
that high testosterone leads to a high conversion rate to estrogens.
In very young athletes HCG, like anabolic steroids, can cause an
early stunting of growth since it prematurely closes the epiphysial
growth plates. Mood swings and high blood pressure can also be
attributed to the intake of HCG. HCG is also suitable as "over
bridge" doping before a competition with doping controls.
HCG form of administration is also unusual. The substance
choriongonadotropin is a white powdery freeze-dried substance which
is usually used as a compress. Based on the low structural stability
of this compress it can easily fall apart, thus giving the
impression of a reduced volume. This is, however, insignificant
since there is neither a loss in effect nor a loss of substance.
Each package, for each HCG ampule, includes another ampule with an
injection solution containing isotonic sodium chloride. This liquid,
after both ampules have been opened in a sterile manner, is injected
into the HCG ampule and mixed with the dried substance. The solution
is then ready for use and should be injected intramuscularly. If
only part of the substance is injected the residual solution should
be stored in the refrigerator. It is not necessary to store the
unmixed HCG in the refrigerator; however, it should be kept out of
light and below a temperature of 25� C.
HCG is a relatively expensive compound. Pregnyl costs approx.$36 -45
for 3 ampules of 5000 I.U. each and the relative solution ampules.
The other compounds have a similar price and are $12 -15 for 5000
I.U. The 5000 I.U. ampules are the most economic and, in our
opinion, also the most sensible for bodybuilders, powerlifters and
weightlifters. There are currently only a few fakes of HCG. Since
the dry substance of HCG is somewhat similar to the dry substance of
Somatropin often "cheap" HCG is sold as "expensive" HGH on the black
market. This circumstance was probably Ben Johnson downfall during
his second positive doping test with his increased testosterone/epitestosterone
value in early 1993 (see also growth hormones HGH).
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